Babesiosis is a tick-borne disease primarily transmitted by the intraerythrocytic protozoa Babesia microti in the U.S., which causes malaria-like symptoms and severe hemolytic anemia that range from being asymptomatic to causing death. With rising incidence of babesiosis and nearly 2000 confirmed babesiosis cases annually in the U.S., clinically validated treatments for babesiosis are needed. RBC exchange transfusions typically remove and…