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Nipocalimab for Severe Hemolytic Disease of the Fetus and Newborn

Hemolytic disease of the fetus and newborn (HDFN) often results in severe anemia resulting in intrauterine transfusions and increased risk of fetal death. According to the recently published phase 2 UNITY study of 13 pregnancies, nipocalimab (a human monoclonal antibody that blocks the Fc receptor) given during pregnancy helps to prevent maternal IgG alloantibodies from crossing the placenta and delays…

2 days ago

Clinical Guidelines for Anemia and Chronic Kidney Disease

  • Ferritin-Guided Donation Policies Decrease Iron Deficiency

  • RBC Transfusions to Treat Acute Heavy Menstrual Bleeding

  • RBC Transfusion Outcomes Similar in ICU Patients with and Without Cardiovascular Disease

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  • Cryopreserved vs. Standard Platelets for Surgical Bleeding

  • Phosphatidylserine and Phosphatidylethanolamine Levels on RBCs Important for Transfusion Outcomes

  • Blood Donation and Improved Cardiometabolic Health

  • Mitochondrial DNA Acts as a “First Hit” for Antibody-Mediated TRALI

  • Liberal or Restrictive Transfusion Thresholds for Surgery Patients with High Cardiac Risk

  • Iron Supplementation for Blood Donors Based on Ferritin Levels

  • Impact of Individual Donor Assessment Deferral Changes on Donor HIV, HBV, HCV, and Syphilis Prevalence

  • RBC Transfusions in Neonatal ICUs Above Restrictive Hb Thresholds

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